It has been four years since the alien-seeking agents averted an intergalactic disaster of epic proportions. Kay has since returned to the comforts of civilian life while Jay continues to work for the Men in Black, the highly funded yet unofficial government agency that regulates all things alien on earth. While investigating a seemingly routine crime, Jay uncovers a diabolical plot masterminded by Serleena, an evil Kylothian monster who disguises herself as a sexy lingerie model. It’s a race against the clock as Jay must convince Kay--who not only has no memory of his time spent with the agency, but is also the only person alive who has the expertise to save the galaxy--to reunite with the MIB before Earth is destroyed completely.